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BCAA supplementation reduces the amount of tryptophan that gets through the blood-brain barrier, and therefore reduces the amount of serotonin produced

doi: 10.1186/s40168-017-0271-9, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 53

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By reducing glutamate levels and oxidative stress in the brain it appears to reduce central nervous system excitotoxicity

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