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As a recent research report, the strong antioxidant resveratrol significantly inhibits the production of ROS, thereby inhibiting oxidative stress, and thus plays a protective effect on PM2.5-induced heart defects in zebrafish embryos (Ren et al., 2020)

Useful for this discussion is a recent meta-analysis of MRS studies, which found that physical activity, rather than sedentary lifestyle, is related to higher brain lactate [81]

PLoS One 12:e0169526

Harrison DG, Gongora MC

Its regarded as an important support for antioxidant balance and cellular protection because of this glutathione connection