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Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver
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In obese subjects, overpopulated immune cells (mainly macrophages) and dysfunctional adipocytes secrete a variety of cytokines and chemokines, causing low-grade long-term inflammation in AT, which plays a determining role in metabolic diseases, such as cardiovascular diseases, liver steatosis and type 2 diabetes [2]
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