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References 1.Barregrd L., Svalander C., Schtz A., Westberg G., Sllsten G., Blohm I., Mlne J., Attman P.O., Haglind P

Genetic inhibition of GCLC enhances ferroptosis due to metabolic stress, including cystine starvation (Gao et al., 2015).GCL links cysteine and Glu to produce -glutamylcysteine (-GC) which is catalyzed to G-SH by GSS

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Neither is currently licensed for routine clinical use in the UK