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The mechanism works through beta-3 adrenergic receptors, which are concentrated in fat tissue, particularly around the abdomen and midsection
Neuropsychopharmacology 1996;15:45664
FDA focused its effectiveness review on ulcerative colitis and found the evidence insufficient
GLP-1-based compounds work primarily through appetite suppression, and the weight loss they produce includes significant lean mass loss (approximately 40% of total weight lost is lean tissue based on STEP trial data)
