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The best non-diabetic body-composition anchor favors tirzepatide, about 75:25 fat-to-lean loss in its DXA data versus about 62:38 in semaglutides. This is cross-trial evidence, not a head-to-head maintenance-dose DXA result

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[DOI] [PubMed] [Google Scholar] 76.Boban-Blagaic A., Blagaic V., Romic Z., Sikiric P

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Comment: Several commenters expressed their support of the approach described in this update, particularly the plan to gather two years of performance data prior to adding a HE adjustment

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