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Nonsignificant changes in HDL-C levels (-0.04 to 0.00 mmol/L) were reported following liraglutide treatment [66]

Dual GIP and GLP-1 receptor agonist tirzepatide improves beta-cell function and insulin sensitivity in type 2 diabetes

Historic examples of such a co-administration therapy for the treatment of obesity include the famous rainbow pills [878]
Heterogeneity in baseline antihypertensive drug use, trial duration, GLP-1 RA dosing, and participant characteristics further limits the comparability and interpretation of BP effects across RCTs

Tanaka M, Matsuo Y, Yamakage H, Masuda S, Terada Y, Muranaka K, Wada H, Hasegawa K, Shimatsu A, Satoh-Asahara N

doi: 10.1042/bj3100203
