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Although there was no expectation that acute loss of function would match that from chronic reduction, we still observed several splicing alterations in the mutant fibroblasts that showed the same trends as the changes produced by FUS/TLS or SMN knockdown

[DOI] [PubMed] [Google Scholar] 162.Gndodu S., Trke C., Arslan M., Demir Y., Beydemir

doi: 10.1016/j.cell.2017.09.044 48 ChuBKonNChenDLiTLiuTJiangLet al

Another mode by which CBS can be modulated is by phosphorylation

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Glutathione acts as a shield, helping to prevent oxidative stress and long-term skin damage