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Activated TGF- inhibits the proliferation and migration of SMC, thus the inhibition of this regulatory effect of TGF- leads to accelerated blood vessel stenosis with concomitant enhancement of the atherogenic process

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Allergic reactions are rare but possible

Strictly speaking, its indicated for people with HIV whove accumulated abdominal fat as a result of antiretroviral therapy, but clinicians have prescribed it off-label to non-HIV patients who want to shed abdominal fat of their own

In the mitochondria it is converted into L-Carnitine and Propionyl Coenzyme A