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Early results of lower dose dasatinib (50?mg daily) as frontline therapy for newly diagnosed chronic-phase chronic myeloid leukemia

This effect may result from T-cell hyporesponsiveness induced by continued ROS exposure, which was induced by imbalance between ROS generation and scavenging through inhibition of antioxidant activity of Gpx1

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*Correspondence: Kun Chen, [email protected] This article was submitted to Cell Death and Survival, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Tang X, Liu J, Yao S, Zheng J, Gong X, Xiao B