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emphasize that future research combining genotype sequencing, pharmacokinetic monitoring, and comprehensive phenotyping (including adverse effects, co-medications, and environmental influences) will be critical to fully elucidate the contribution of CYP2D6 and CYP2C19 polymorphisms to individualized antidepressant therapy

1938 - 1939 Journal articles | 2003 Gooding JJ

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From a systems perspective, anxiety disorders is characterized by abnormalities in neurotransmitter functions, neurotrophic signaling, the endocannabinoid system and HPA axis function and these alterations are further compounded by chronic inflammation and maladaptive immune responses (Mac Giollabhui et al., 2025), while epidemiological data show that individuals with inflammatory autoimmune diseases like psoriasis have increased risks of experiencing developing anxiety disorders (Lee et al., 2025)

A recent open-label RCT investigated the effects of adding rifaximin to SOC in patients with SAH [95]

Periquet M, Corti O, Jacquier S, Brice A (2005) Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function