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Description
The authors suggest that inhibition of FAO may lead to an overall decrease in cancer cell survival, while an increase in CPT1 activity, such as the PRL-mediated response, may provide a supportive environment for malignant cells 36
Mundinger, TO
The acetyl-CoA can enter the tricarboxylic acid (TCA) cycle for production of reducing equivalents for oxidative phosphorylation resulting in ATP production, or may enter the ketone body synthesis pathway in the liver
Accessed 13 Jan
Pettegrew J, Levine J, McClure R
Cancer Cell 19 , 575586 (2011)
