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doi: 10.1111/j.1365-2249.2007.03441.x

With a fixed 70 mg vial, the dose per IU depends entirely on the reconstitution volume the researcher chooses

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It was first isolated in 1974 from cerebral venous blood during induced sleep states

This is because endotoxins may introduce unwanted variables into laboratory studies and cause biological contamination, affecting experimental reproducibility

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