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Researchers also found that decreasing NNMT caused a 47% reduction in the mices fat mass

Shea / AFP / Getty Read more Andrew White helps a neighbor down a street after rescuing her from her home in his boat in the River Oaks neighborhood after it was inundated with flooding from Hurricane Harvey on August 27, 2017

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A 2025 intravenous safety study involving two healthy adults found infusions up to 20 mg well tolerated, with no adverse events or clinically meaningful changes in vital signs or laboratory biomarkers