glutathione metabolism cell death Multiomics reveals as a driver of bimodality during stem aging: Cell Metabolism A comprehensive overview of recent
Description
SLC7A11 gene translation is finely transcriptionally directed, with oxygen exhaustion and amino acid depletion conditions stimulating factor, hence dependently inducing its production
Glutathione depletion by BSO does not affect FAC-induced mitochondrial LPO but strongly stimulates the accumulation of ROS in the cytosol
Daily JW, Yang M, Kim DS, Park S
Working Concentrations Reported in the Literature For researchers designing in-vitro protocols, published concentration ranges provide a useful starting reference point (though any specific protocol should be validated against the relevant primary literature for the assay in question)
They demonstrated an increase in specific LPO parameters such as ethane and pentane exhalation by 30- to-50-fold, accompanied by GSH depletion and loss of PUFAs (mainly 20:4 and 22:6)
Anticonvulsant and anxiolytic evaluation of leaf extracts of Ocimum gratissimum, a culinary herb pharmacognosy research
