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139 On the pathogenic side, hepatic accumulation of FFAs, oxidative stress, and gut barrier dysfunction lead to LPS translocation, activating the NLRP3 inflammasome

Taken together, these data show that transgenic expression of the APOE4 protein dysregulated the expression characteristics of the Pin1 , Sirt1 , and PS1 genes in different brain areas and the observed differences might contribute to the increased AD vulnerability of APOE4 mice

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J., Brach, T., Marty, L., Kreye, S., Rouhier, N., Jacquot, J

doi: 10.1016/j.jfca.2024.105981 16

Wire Nets Set Against Supposed Man-Eater That Killed Spring Lake Bather," The New York Times , July 8, 1916, p