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The possible mechanisms that account for the beneficial response seen with L-carnitine in AMI are probably multifactorial and include, in part, an improvement in myocardial mitochondrial energy metabolism in the heart due to its ability to enhance the transport of long-chain fatty acids from the cytosol to the mitochondrial matrix where -oxidation occurs, removing toxic fatty acid intermediates, lessening ischemia secondary to elevated long-chain fatty acid concentrations, and replenishing the depleted carnitine concentrations seen in ischemic, infarct, and failing myocardium
Alcohol Res Health 27:240246 Butterworth RF (2012) Brain edema and encephalopathy in acute liver failure: a primary neurogliopathy
A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer
10.3389/fendo.2023.1085041 188 ZhouH.ZhaoJ.LiuC.ZhangZ.ZhangY.MengD
