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34 EphA4 knockout mice have dramatically reduced body size and impaired GHR signaling: they have normal levels of GH mRNA expression in the pituitary but have reduced plasma IGF1 and reduced IGF1 mRNA expression in the liver

Aging Pathobiology and Therapeutics , 2020

The expected normal value is zero at all ages

This superficial location makes them vulnerable to repetitive strain but also makes them accessible for local treatment approaches

N., Martins S

When used correctly, side effects are rare
