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The amino group of NE or DA forms two hydrogen bonds, one with the carboxyl group of Glu382 and the other with the carbonyl group of Lys88

158 In addition to using zinc chelators to inhibit the proliferative growth of cancer tissues, 78,159161 another potential approach is to use ZIP6 or ZIP10-blocking antibodies to hinder mitosis in cancer progression
compounding pharmacies may legally prepare them again under physician oversight

Deferoxamine, a widely used iron chelator, has proven effective in treating iron overload-related disorders but carries significant side effects, particularly affecting renal function and the immune system (179, 180)

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Despite the wide variety of malignancies studied, many of the works just employ tumoral cell lines but lack validation of the results in preclinical animal models
