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5.Validation of analytical methods
& Yoshino, J

This lowers intraluminal colon pressure and anal pressure both of which decrease the risk of developing diverticula and hemorrhoids

But almost all of the serious complications cluster in patients who were started at high doses and escalated aggressively

doi: 10.1016/j.neuint.2019.04.006 [DOI] [PubMed] [Google Scholar] 37.Kleinridders A, Cai W, Cappellucci L, et al
