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Studies have shown that high doses of PPR (e.g., 10 mg/kg) significantly reduce sperm motility, concentration, and viability in adult male rats, with adverse effects on key reproductive markers and antioxidant enzymes (70, 71)

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Hair counts offer quantitative data but require significant effort

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Lactylation modifications of non-histone proteins may be of great interest for future research, even if no relevant reports are currently available (Sun L

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& Axelrod, L

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Funding Independent investigator-initiated grant provided by Biogen Pharmaceuticals Pty Ltd

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