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Modulation of Tyrosinase Expression Tyrosinase gene expression, together with Tyrp1 and Typr2, is induced by microphthalmia transcription factor (MITF), which is in turn regulated by signaling pathways, including cAMP/PKA/CREB, RAS/MEK/ERK, and -catenin pathways
These effects promote SCFA production, protect the intestines system, and regulate multiple metabolic and immune processes in organisms through activation of the P38MAPK/PGC-1/GLUT4 and Akt/AS160/GLUT4 signaling pathways, suggesting that baicalin may be a promising therapeutic agent for metabolic disorders [118, 119]
World J Gastroenterol (2020) 26(38):5759
Liposome-based engineering of cells to package hydrophobic compounds in membrane vesicles for tumor penetration
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