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Retatrutide Phase 3 TRIUMPH-4 data (December 2025): 28.7% mean weight loss at 68 weeks with 12 mg

In the open-field test, line crossings and rearing behaviors were restored significantly in the 100 mg/kg group, indicating improved exploratory activity

Li Y, Chen J, Wang L, Zhang L, Lu M, Chopp M

B.JohnstonP

A significant (P = 0.003) increase in the CBL gene was seen in egtA 26933 compared to wild-type under ROS conditions

doi: 10.1016/j.ceb.2014.03.005
