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10.1007/s11010-016-2729-7 47 RioloG.CantaraS.MarzocchiC.RicciC

Human Growth Hormone (HGH) is a naturally occurring peptide hormone secreted by the pituitary gland

Furthermore, treatment with N-acetyl-L-cysteine also decreased Akt phosphorylation in GPx1 deficient cells

Cellular metabolism

Amino acid dependent formaldehyde metabolism in mammals

We have solved the structures of the pi class GST hP1-1 in complex with its substrate, glutathione, a transition-state complex, the Meisenheimer complex, and an inhibitor, S-(rho-bromobenzyl)-glutathione, and refined them to resolutions of 1.8 A, 2.0 A and 1.9 A, respectively