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4.4 Summary of the integrated testicular-penile pathological axis The mechanisms described above suggest that varicocele may contribute to ED through a multi-level testicularpenile pathological axis centered on inflammation, oxidative stress, vascular dysfunction, smooth muscle remodeling, and neural injury (111)

Type 2 diabetes refers to the common form of idiopathic NIDDM

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The probability of ALN manifestation increases with the duration of alcohol abuse [77, 78]

At least one well-designed study suggests that carnitine supplements may improve muscle function and exercise capacity in those with PVD

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