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(PubMed) 26

Zonulin-dependent activation of PAR2 reinforces EGFR signaling, which further activates PKC and leads to the phosphorylation of ZO-1 and myosin 1C (52)

10.3389/fmicb.2022.1103836 230

doi: 10.1096/fj.14-253633
Next, we detected the GPX4 and FTH1 levels in colorectal cancer patients undergoing neoadjuvant chemoradiotherapy by immunohistochemistry, and found both protein levels were up-regulated, compared with the patients without neoadjuvant chemoradiotherapy ( Figure 6A )

By analyzing RNA sequencing data, we found the increase in ATF4-mediated transcriptional network for the upregulation of SHMT2 for dTTP in T315I-Bcr-Abl-32D cells
