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Reporter gene assay data suggests RUNX1 has a stronger suppressive effect on the minor rs2268277 allele (58)

Och, A., Och, M., Nowak, R., Podgrska, D., & Podgrski, R

In a study investigating associations between polymorphisms in the glutathione-S-transferase genes GSTT1 , GSTM1 , GSTP1 and an increased risk of acetaminophen poisoning, prothrombin time was used as a marker of survival in poisoned patients [91]

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Debonnaire P., Delgado V., Bax J.J

Nonalcoholic fatty liver disease: pathogenesis and the role of antioxidants

It also raises stress hormones, which lowers glutathione action in a roundabout way