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Gastroenterology 160 , 831846

The threshold cycle value (CT) was determined for each measurement, and mRNA expression was calculated relative to the control using the comparative critical threshold (2 CT) method, where CT = CTmRNA CThousekeeping control

Second, while CYP3A4 was extensively validated in functional assays, other key markers of liver functionality, such as bile acid transporters and detoxification enzymes, were not examined in as much detail

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However, B12 levels can rise regardless of whether treatment is effective

The 4 stages of B12 deficiency are as follows: Stage 1: Low levels of vitamin B12 on blood test, but no symptoms