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Description
ROS , Reactive oxygen species
10.1021/acs.oprd.3c00136 29 CaiH.YipV.LeeM

In addition, astrocytes appear to be the major source of -Glu-AAs (Figure 5)

KLOW adds a fourth peptide, KPV

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Regarding iron metabolism, intracellular and extracellular ALDH2 decreases 4-HNE, activates the Nrf2/HO-1 pathway to decrease intracellular iron accumulation and mitigates hepatic cell ferroptosis through Parkin-mediated mitochondrial autophagy (131)
