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Epigenetic modulation of gene expression by dietary isothiocyanates Despite the fact that most work on the cellular effects of ITC relates to their influence on detoxifying enzymes, recent data support the effect of these dietary compounds on the reactivation of epigenetically silenced genes in cancer cells, particularly through the inhibition of HDAC activity ( Reference Dashwood and Ho 52 )

doi:10.3390/molecules25112655 [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Turbic A, Ahokas JT, Haskard CA

Lignans have also been found to alleviate inflammatory phenotype and OS induced by high glucose (HG) in various cellular models

157 Activation of NLRP3 inflammasome Canonical activation of NLRP3 inflammasome involves two hits: priming and activation

Plant Physiol Biochem 103:1023 Cao L, Karapetyan S, Yoo H, Chen T, Mwimba M, Zhang X, Dong X (2024) H 2 O 2 sulfenylates CHE, linking local infection to the establishment of systemic acquired resistance
2 Hydrogen peroxide in the peroxisome and the mitochondria: a source of deupleted water
