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10.1111/j.1365-2265.1992.tb02909.x 32

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Further Studies of Vitamin E, Thyroid and Heart Health Thyroid hormones are associated with the oxidative and antioxidative status of the body, and one study that investigated the oxidant and antioxidant effects on rats found that hypothyroidism is accompanied by increased oxidative stress, but vitamin E supplementation exerts beneficial effects on this situation

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Pb exposure has been widely associated with increased generation of ROS and reactive nitrogen species (RNS), mainly due to its interference with mitochondrial respiration and its ability to displace essential divalent cations (e.g., Ca 2+ and Zn 2+ ) [62,97]
