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Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model

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Oh U, Woolbright E, Lehner-Gulotta D, Coleman R, Conaway M, Goldman MD, et al

This induction accelerates the clearance of drugs that rely on UGT-mediated metabolism (e.g., capecitabine), potentially resulting in insufficient therapeutic exposure to the chemotherapeutic agent and thereby impairing its antitumor efficacy
