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[Abstract] Adv Sci (Weinh)

At the periphery of the lobules, there are smaller, stellate cells with eosinophilic cytoplasm

While vaginal mucus provides some protection against viral entry, the thin mucus lining of the rectum allows direct access to leukocytes (Morrow et al., 2007)

For example, lactate can activate the HIF-1 pathway in microglia to enhance pro-inflammatory cytokine release, while IL-1 can inhibit neuronal PGC-1 expression to impair mitochondrial biogenesis, forming a potential link between peripheral immune metabolic reprogramming and central neuroinflammation and energy deficiency