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Approval was obtained from each participating center's internal review board

Many robust clinical trials show that by increasing the body's Carnitine stores through supplementation, the body is able to transport the fatty acids more rapidly into the mitochondria, allowing for a more efficient energy metabolism and hence delayed fatigue

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[DOI] [PubMed] [Google Scholar] 228.Celli R., Santolini I., Van Luijtelaar G., Ngomba R.T., Bruno V., Nicoletti F

Faverzani JL, Hammerschmidt TG, Mescka CP, Guerreiro G, Lopes FF, Delgado CA, de Moura Coelho D, Sitta A, Deon M, Wajner M, Vargas CR (2023) Increased cytokine levels induced by high phenylalanine concentrations in late diagnosis PKU patients compared to early diagnosis: anti-inflammatory effect of L-carnitine

PPAR is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues