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PEPITEM, its tripeptide pharmacophores and their peptidomimetic analogues regulate the inflammatory response through parenteral and topical dosing in models of peritonitis and psoriasis

7 (Suppl 3):S111-8 9

Pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) expressed on epithelial cells interact with microbiota-derived pathogen-associated-molecular patterns (PAMPs) such as lipopolysaccharide (LPS) to activate myeloid differentiation factor 88 (MYD88)-dependent signaling

Takahashi K, Kameda H, Kataoka M, Sanjou K, Harata N, Akaike N

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