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an overview of preclinical and clinical studies performed can be found in Table 1 and Table 2, respectively

B.AurilioC.SansoneP.AurilioR.DE MariaS.et al (2015)

242 Additionally, UNA modification at the siRNA terminus improves siRNA stability and silencing efficacy while considerably reducing off-target effects, highlighting its potential in the development of new therapeutic siRNAs

It acts as a signaling molecule that tells the body to prioritize the repair of damaged dermal and subcutaneous tissues

After 48 h, cells were fixed with 4% PFA for 45 min and then stained with DAPI for 15 min

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