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This hypothesis is supported by post-mortem evidence of reduced pyruvate dehydrogenase activity in the brains of individuals with ASD (Gu et al., 2013), which may impair the conversion of pyruvate to acetyl-CoA, leading to mitochondrial dysfunction and accumulation of lactate and alanine

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Glucose-lipid metabolic parameters were compared, and VC status before and 6 and 12 months after LSG were measured
10.1016/S0893-133X(02)00306-8 [DOI] [PubMed] [Google Scholar] 97.Piovesan P, Pacifici L, Taglialatela G, Ramacci MT, Angelucci L

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Guo et al (7678) showed FSP1 inhibits ferroptosis by generating antioxidant CoQ, reducing intracellular oxidized CoQ