glutathione bipolar depression Therapeutic potential of glutathione-enhancers in stress-related psychopathologies In vivo glutathione levels in
Description
Combined inhibition of glutamine utilization and BCL2 triggered rapid apoptosis, providing a rationale for tailored therapeutic strategies in NOTCH1 -mutated CLL

2020 Apr 15;70(9):1799-1808

Sharma M, Rajendrarao S, Shahani N, Ramrez-Jarqun UN, Subramaniam S

Five delivered real results

Within the mitochondria itaconate inhibits the succinate dehydrogenase (SDH) complex which results in reduced flow of carbons through the TCA cycle as well as inhibition of oxidative phosphorylation since TCA cycle SDH is also complex II of the electron transport chain

10.1073/pnas.1115402109 137 GuerreroE
