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Vitamin B-12 Is required for the development and function of the central nervous system Is necessary for the formation of red blood cells and DNA Is involved in the breakdown of a protein called homocysteine, which is associated with an increased risk of heart disease and stroke Helps maintain healthy nerve cells and is involved in the production of DNA and RNA Works closely with vitamin B9 (folate or folic acid) to help make red blood cells and to help iron work better in the body Aids in the production of S-adenosylmethionine (SAMe), a compound involved in immune function and mood Vitamin B-12 deficiency is relatively common, and studies show that in the United States, approximately 6% of adults under 60 have a vitamin B12 deficiency, and close to 20% of those older than 60

These systems can model neurovascularglial interactions, BBB dysfunction and the combined astrocytemicroglia effects on oligodendrocyte survival and myelination, thereby enabling concurrent assessment of neuronal health, myelin dynamics, immune activation and vascular integrity with high experimental accessibility

It is often associated with skin-brightening effects and is widely used to help maintain an even skin tone

The future of age-related diseases treatment is linked to the development of new approaches based on cell therapy or immunotherapy to offer the best treatment for patients

Huang HY, Helzlsouer KJ, Appel LJ

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