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Cellular iron uptake, trafficking and metabolism: key molecules and mechanisms and their roles in disease

doi: 10.1002/jobm.201900382

Five years later (in 2008), the importance of ferrous iron, the system xc - (xCT) controlled cystine/cysteine redox cycle, and the glutathione peroxidase 4 (GPX4)-glutathione (GSH) redox system in lipid peroxidation and non-apoptotic cell death was highlighted by different research groups[10-12]

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CircRNA expression profiles of vitiligo patients before and after systemic glucocorticoids treatment were significantly different, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways revealed that the down-regulated differential circRNAs were predominantly enriched in ferroptosis regulatory pathways

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