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In the breast cancer lung metastasis model, the platelet-derived growth factor C (PDGF-C) level in the microenvironment increases when lung tissue becomes senescent or fibrotic

If the true reporting rate is 5%, then the 520 reported events suggest approximately 10,400 actual adverse events

doi: 10.1038/s41398-022-02227-y 72 HoepnerC

While the most extensive Vitamin E studies have been performed on diabetics with higher levels of oxidative stress, researchers have found a link between supplements and increased glutathione levels

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For accurate reporting, relevant data items extracted from each RCT included the name and year of publication, the country where the study was performed, sample and gender dissemination, as well as the dose and duration of intervention