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[14] demonstrated that NNMT is a positive modulator in hepatocyte gluconeogenesis but the roles of NNMT in glycogen metabolism in the liver and the mechanisms by which NNMT affects insulin sensitivity have not yet been reported

Some ideas: if ibuprofen isnt getting the job done, ask about a COX-2 inhibitor like Celebrex

[DOI] [PubMed] [Google Scholar] 94.Nadeem A., Siddiqui N., Alharbi N.O., Alharbi M.M., Imam F., Sayed-Ahmed M.M

That means it's safer for long-term use while still helping reduce swelling, pain, and tissue breakdown

Regarding chondrogenic/NP-like differentiation, existing research results show some divergence

Efficacy and safety of a topical botanical in female androgenetic alopecia: a randomized, single-blinded, vehicle-controlled study