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doi: 10.1016/j.cell.2011.02.013 83 El-KhamisySFSaifiGMWeinfeldMJohanssonFHelledayTLupskiJRet al

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Enhancing inhibitory signals in the pain pathway: vitamin B12 has been found to increase the effectiveness of norepinephrine and 5-hydroxytryptamine as inhibitory signals in the pain pathway, resulting in reduced pain perception
That does not mean that we can say for sure that vitamin B12 deficiency doesnt cause joint pain, just that the evidence is not there yet

This is an interesting topic I will discuss in another blog

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