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doi: 10.1016/j.cell.2011.02.013 83 El-KhamisySFSaifiGMWeinfeldMJohanssonFHelledayTLupskiJRet al

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Enhancing inhibitory signals in the pain pathway: vitamin B12 has been found to increase the effectiveness of norepinephrine and 5-hydroxytryptamine as inhibitory signals in the pain pathway, resulting in reduced pain perception

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That does not mean that we can say for sure that vitamin B12 deficiency doesnt cause joint pain, just that the evidence is not there yet

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This is an interesting topic I will discuss in another blog

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