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Although the precise etiology of SS remains unclear, recent technological advancements have highlighted the critical role of lipid metabolism and dyslipidemia in the development of SS, offering new insights into its pathogenesis [22]

doi: 10.1038/nature05894 71 KangKReillySMKarabacakVGanglMRFitzgeraldKHatanoBet al

Besides, the other randomized control trial is also being performed by National Taiwan University Hospital to investigate the effect of prednisolone as an adjunct therapy to improve the symptoms worsening in patients with tuberculous lymphadenitis (ClinicalTrials.gov Identifier: NCT05861440)

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Due to the shortened C-terminus, the archaeal enzyme structures lack hydrogen bonds, which are formed between amino acids (Lys426 and Tyr430) of one subunit with the 2- and 3-hydroxy groups of the adenosine moiety and the pyrophosphate of NAD + bound in the adjacent subunit, present in Mm SAHH and other mesophilic homologues
