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(data represented as meanS.D.).

This specificity theoretically supports a favorable safety profile, though human data remains limited

In silico predictive modeling Based on the binding pose observed for THC in the X-ray structure, we used the program DOCK 28 to computationally predict binding geometries of the primary THC metabolite 11-OH-THC, secondary THC metabolite THC-COOH, the THC isomer CBD, and the cannabinoid analog AJA

N-acetylcysteine (NAC), a bioavailable cysteine donor, can support endogenous GSH synthesis and may also exert antioxidant effects independent of GSH replenishment

Hydrate and cool down

In the endogenous apoptotic pathway, various cellular stress, such as nuclear DNA damage, cytokine deprivation, endoplasmic reticulum stress (ERs), lysosomal permeabilization, and oxidative stress generate intracellular death signals to promote mitochondrial dysfunction and subsequently mitochondrial outer membrane pore formation (MOMP)