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Phlebitis: Vein inflammation can cause pain and redness along the vein

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When to Seek Help For a Herxheimer Reaction or Healing Crisis While Herxheimer reactions are typically temporary and a sign of progress, consult your healthcare provider if you experience: Severe or prolonged symptoms Difficulty breathing or swelling (potential allergic reaction) Extreme fatigue or dehydration The Healing Crisis: A Sign of Progress A Herxheimer reaction, while uncomfortable, is often a positive sign that your body is actively working to heal