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Singly-housing animals, which prevents inter-animal coprophagy, reduces beta diversity of the microbiome compared to stressful (chronic subordinate colony) co-housing conditions 72

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1 week (1 vial): 4 mL 1 10 mL bottle 2 weeks (1 vial): 4 mL 1 10 mL bottle 4 weeks (2 vials): 8 mL 1 10 mL bottle Alcohol Swabs: One for the vial stopper + one for the injection site each administration

The second is dose and route translation : even where an effect is real in a mouse, the human-equivalent dose is not a simple body-weight scaling, and as the route section above stressed there is no human bioavailability figure to anchor an oral-versus-injected comparison

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Preclinical work in obese murine models suggests that encapsulated 5-Amino-1MQ administration led to decreases in overall body weight and reductions in white adipose mass