n4-sulfone-sulfamethoxazole-glutathione conjugate Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Metabolism of sulfamethoxazole in Arabidopsis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Harmar AJ, Arimura A, Gozes I, Journot L, Laburthe M, Pisegna JR, Rawlings SR, Robberecht P, Said SI, Sreedharan SP, Wank SA, Waschek JA

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This pathological iron overload provides a continuous substrate for the Fenton reaction, constituting a fundamental and persistent risk factor driving lipid peroxidation and inducing ferroptosis (Zhang Y