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Metabolic Regulation & Obesity Research

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See online supplementary Methods for primary and secondary endpoints, exclusion criteria, and data analyses

EMBO Mol Med 15:EMMM202217052-

Retatrutide reconstitution chart Vial Size 5 mg BAC Water 1.0 mL Concentration 5 mg/mL (5,000 mcg/mL) 1 mg 0.20 mL (20 units) 2 mg 0.40 mL (40 units) 4 mg 0.80 mL (80 units) 6 mg Exceeds vial 9 mg Exceeds vial 12 mg Exceeds vial Vial Size 10 mg BAC Water 2.0 mL Concentration 5 mg/mL (5,000 mcg/mL) 1 mg 0.20 mL (20 units) 2 mg 0.40 mL (40 units) 4 mg 0.80 mL (80 units) 6 mg 1.20 mL - split draw or 2 vials 9 mg Requires 2 vials 12 mg Requires 2-3 vials Vial Size 20 mg BAC Water 2.0 mL Concentration 10 mg/mL (10,000 mcg/mL) 1 mg 0.10 mL (10 units) 2 mg 0.20 mL (20 units) 4 mg 0.40 mL (40 units) 6 mg 0.60 mL (60 units) 9 mg 0.90 mL (90 units) 12 mg 1.20 mL - split draw Vial Size 24 mg BAC Water 2.4 mL Concentration 10 mg/mL (10,000 mcg/mL) 1 mg 0.10 mL (10 units) 2 mg 0.20 mL (20 units) 4 mg 0.40 mL (40 units) 6 mg 0.60 mL (60 units) 9 mg 0.90 mL (90 units) 12 mg 1.20 mL - split draw Vial Size 30 mg BAC Water 3.0 mL Concentration 10 mg/mL (10,000 mcg/mL) 1 mg 0.10 mL (10 units) 2 mg 0.20 mL (20 units) 4 mg 0.40 mL (40 units) 6 mg 0.60 mL (60 units) 9 mg 0.90 mL (90 units) 12 mg 1.20 mL - split draw Units are U-100 insulin syringe units (1 mL = 100 units)