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In degenerative chondrocytes, elevated IL-6 expression triggers lipid peroxidation and iron imbalance via the IL-6/miR-10a-5p/IL-6R axis, thereby promoting ferroptosis and exacerbating inflammation associated with intervertebral disc degeneration (Jeong et al., 2003)

Khan et al., 2021)

Li JQ, Welchowski T, Schmid M, Mauschitz MM, Holz FG, Finger RP

Ochratoxin A: molecular interactions, mechanisms of toxicity and prevention at the molecular level

Age-related accumulation of Ig V(H) gene somatic mutations in peripheral B cells from aged humans

However, after adjustment for covariates (age, height, pack-years, BMI, and season), these relationships were no longer statistically significant (FEV 1 , P = 0.15